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Hericium Erinaceus
Extract

Moderate study situation·7/10
A higher score indicates better study conditions, but not necessarily effectiveness.

Hericium erinaceus (Lion’s Mane) extract is a fungus supplement with emerging evidence supporting cognitive, neuroprotective, and mood benefits.

Anti-inflammatoryCognitive EnhancementDepression / Mood EnhancementNeuroprotectiveAnxiety Relief
dose range
1000–3000 mg
Divide into 1–3 doses per day.
Consumption
Take with food to support absorption and minimize digestive side effects.
Not fat-soluble.
Best time
Morning or with the first meal is commonly suggested.

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Description

Hericium erinaceus, known as Lion’s Mane, is an edible mushroom traditionally used in Asian medicine. Its extracts, derived from fruiting bodies or mycelium, are consumed to support brain health and overall wellness.

benefits
Main effects with level of evidence
Moderate
Note on evidence

Human trials support cognitive and mood benefits, but more large-scale studies are needed for confirmation. Mechanistic and animal data are stronger.

Cognitive Function Support

Moderate

Supplementation may help improve cognitive performance, especially in mild cognitive impairment, possibly by stimulating nerve growth factor (NGF) production.

Particularly relevant for: Older adults · People seeking cognitive support
1 · PubMed: Nagano et al. (2008)2 · PubMed: Mori et al. (2014)6 · Examine.com: Lion's Mane Mushroom

Mood and Anxiety Relief

Limited

May reduce symptoms of anxiety and depression, with effects suggested in early human trials and linked to anti-inflammatory and neurogenic mechanisms.

Particularly relevant for: Those with mild mood disturbances · Menopausal women
3 · PubMed: Nagano et al. (2010)6 · Examine.com: Lion's Mane Mushroom

Neuroprotection

Theoretical

Promotes synthesis of NGF and may support nerve regeneration, potentially benefiting those with neuropathy or neurodegenerative conditions.

Particularly relevant for: Individuals at risk for neurodegeneration
2 · PubMed: Mori et al. (2014)6 · Examine.com: Lion's Mane Mushroom

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This information is for educational purposes only and does not replace medical advice.
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This website is for educational and informational purposes only and does not constitute medical advice or professional services. The information provided should not be used to diagnose or treat any health problem or disease. Persons requiring medical advice should consult a licensed physician.