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Licorice Root

Mixed study results·5/10
A higher score indicates better study conditions, but not necessarily effectiveness.

Licorice root is an herbal extract traditionally used for digestion, inflammation, respiratory support, and stress, but can increase blood pressure and affect potassium levels.

dose range
100–600 mg
1–2 divided doses daily
Consumption
Take standardized licorice root extract (by glycyrrhizin content) with or between meals. DGL forms are preferable for digestive health if avoiding glycyrrhizin side effects.
Not fat-soluble.
Best time
Limit duration to a few weeks unless supervised. Avoid high doses or long-term use unless physician-monitored.
Description

Licorice root (Glycyrrhiza glabra) has been used in traditional medicine systems for centuries for a variety of ailments, including digestive discomfort, respiratory issues, and inflammation. The main bioactive compound, glycyrrhizin, has pharmacological effects but can also cause significant side effects if overused.

benefits
Main effects with level of evidence
Mixed
Note on evidence

Some traditional benefits are supported by preclinical or emerging human evidence, but high-quality clinical trials are limited and there are safety concerns with prolonged or high-dose use.

May support digestion and help soothe gastrointestinal discomfort

Moderate

Licorice root may be beneficial for mild digestive issues such as heartburn and stomach upset, especially as deglycyrrhizinated licorice (DGL).

Particularly relevant for: adults with occasional digestive upset

May have anti-inflammatory properties

Limited

Bioactive compounds in licorice root show anti-inflammatory effects in preclinical models, potentially contributing to symptom relief in conditions like sore throat or minor gastrointestinal inflammation.

Particularly relevant for: adults with inflammation-related discomfort

Traditional use for respiratory health

Limited

Licorice root is a traditional remedy for coughs and sore throats, and limited evidence suggests some effectiveness as a soothing agent for respiratory issues.

Particularly relevant for: adults with minor upper respiratory symptoms

Possible liver protection effects

Limited

Some studies suggest liver-protective effects, particularly in settings of toxicity, though evidence in humans is preliminary.

Particularly relevant for: individuals at risk of hepatic stress

Traditional adaptogen for stress relief

Limited

Licorice root has adaptogenic uses in traditional medicine, though robust clinical evidence for stress or adrenal support is lacking.

Particularly relevant for: adults interested in herbal adaptogens

Contains antioxidant compounds

Theoretical

Licorice root contains flavonoids and triterpenoids with antioxidant activity, though clinical significance is uncertain.

Particularly relevant for: general

Last updated:

This information is for educational purposes only and does not replace medical advice.

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This website is for educational and informational purposes only and does not constitute medical advice or professional services. The information provided should not be used to diagnose or treat any health problem or disease. Persons requiring medical advice should consult a licensed physician.