What is Raspberry Extract?

Raspberry Extract is derived from red raspberries and may be standardized for raspberry ketone. It can also contain polyphenols and other plant compounds found in the fruit.

Does Raspberry Extract help with weight loss?

Raspberry Extract is marketed for weight management, largely due to raspberry ketone. Evidence from human studies is limited, so results are not reliable or consistent.

What are the antioxidant benefits of Raspberry Extract?

Raspberry Extract contains polyphenols that show antioxidant activity in laboratory testing. Whether this translates into meaningful health effects in humans depends on the product and dose.

What is a typical dosage for Raspberry Extract?

Common supplemental amounts are around 100–200 mg per day, depending on standardization and formulation. Follow the product label and consult a clinician if you have medical conditions or take medications.

Is Raspberry Extract safe?

Safety depends on the specific extract and dose, and long-term data are limited. People who are pregnant or breastfeeding, or who have medical conditions, should seek medical advice before use.

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Raspberry
Extract

Limited research available·3/10

A higher score indicates better study conditions, but not necessarily effectiveness.

Raspberry extract, often standardized for raspberry ketone, is a supplement studied for potential weight management, antioxidant effects, and skin health, though robust human evidence is limited.

Anti-Aging Antioxidant Skin Health Weight Management

dose range

100–200 mg

Split between two doses daily

Consumption

Take orally with meals for best tolerance; follow supplement-specific instructions.

Not fat-soluble.

Best time

Best taken with meals to reduce risk of gastrointestinal or stimulant-like side effects.

Description

Raspberry extract is derived from the fruit of red raspberries and is widely marketed for weight loss, antioxidant benefits, and skin health. The primary bioactive compound is raspberry ketone, though it also contains a range of polyphenols and vitamins.

benefits

Main effects with level of evidence

Limited

Note on evidence

Most claims are based on animal or in vitro data; human clinical studies remain scarce and results are inconclusive.

Potential support for weight management

Limited

Preclinical studies suggest raspberry ketone may support fat metabolism and weight loss, but human evidence is preliminary and unconvincing.

Particularly relevant for: adults seeking weight management support

2 · PubMed: Raspberry ketone regulates expression of adiponectin and increases fatty acid oxidation in 3T3-L1 adipocytes and C57BL/6 mice 5 · NIH National Center for Complementary and Integrative Health: Dietary Supplements for Weight Loss 6 · Examine.com: Raspberry Ketone

Antioxidant activity

Limited

Raspberry extract's polyphenols display antioxidant properties in vitro and may help reduce oxidative stress.

Particularly relevant for: general adult population

3 · PubMed: Antioxidant activity and polyphenol content of red raspberry extracts 6 · Examine.com: Raspberry Ketone

Skin health and anti-aging

Limited

Raspberry extract (especially topical) may promote skin elasticity and vitality, with one small clinical trial supporting effects via IGF-I upregulation.

Particularly relevant for: individuals seeking skin and hair health improvement

4 · PubMed: Topical application of raspberry extract improves skin cell function and elasticity via IGF-I upregulation 6 · Examine.com: Raspberry Ketone

Safety & Information

Important safety information & known risks

For educational purposes only • not medical advice

Limited safety data are available; possible adverse effects include stimulant-like symptoms and altered blood pressure; caution advised in sensitive groups.

warning notices

High doses may cause jitteriness, palpitations, or elevated blood pressure.
Should not be used during pregnancy or breastfeeding due to lack of safety data.
Individuals with heart conditions, hypertension, or thyroid disorders should exercise caution.
Avoid use if pregnant or breastfeeding due to insufficient safety data.
Do not use if you have heart conditions such as arrhythmias or uncontrolled hypertension.
Monitor blood pressure during use, especially in those with cardiovascular risk.
Avoid combining with medications that affect hormone levels (including thyroid medications) without medical supervision.

Known interactions with medications

thyroid medications
antihypertensive agents

Contraindications / special precautions

pregnant or breastfeeding women
individuals with uncontrolled heart disease or arrhythmias

interactions

Important interactions between active ingredient ↔ supplement / medication / food

Potential interactions with medications affecting hormone levels and cardiovascular system; limited direct nutrient–nutrient interactions are documented.

Potential interaction with thyroid hormone medications

drug · thyroid medication

CautionLimited

Why

Raspberry ketone's structural similarity to stimulants could theoretically affect thyroid hormone metabolism.

recommendation

Consult a clinician before combining raspberry extract with thyroid medications.

1 · WebMD: Raspberry Ketone 5 · NIH National Center for Complementary and Integrative Health: Dietary Supplements for Weight Loss 6 · Examine.com: Raspberry Ketone

May increase blood pressure

drug · blood pressure medication

MonitorLimited

Why

Some users report stimulant-like side effects including increased blood pressure and palpitations.

recommendation

Monitor blood pressure if using raspberry extract alongside hypertension medication.

1 · WebMD: Raspberry Ketone 5 · NIH National Center for Complementary and Integrative Health: Dietary Supplements for Weight Loss

mechanisms of action

Brief explanations of how it works

Modulation of fat metabolism via adiponectin regulation

Animal studies suggest raspberry ketone increases adiponectin expression and enhances fat oxidation; translation to humans is not established.

2 · PubMed: Raspberry ketone regulates expression of adiponectin and increases fatty acid oxidation in 3T3-L1 adipocytes and C57BL/6 mice 6 · Examine.com: Raspberry Ketone

Antioxidant activity through polyphenol content

Polyphenolic compounds in raspberry extract scavenge free radicals and reduce oxidative stress in laboratory studies.

3 · PubMed: Antioxidant activity and polyphenol content of red raspberry extracts 6 · Examine.com: Raspberry Ketone

Potential upregulation of IGF-I for skin elasticity

Topical raspberry extract increased IGF-I expression and improved skin elasticity in a small human study.

4 · PubMed: Topical application of raspberry extract improves skin cell function and elasticity via IGF-I upregulation

Sources & References

Primary literature and reviews on which these statements are based

6 sources

WebMD: Raspberry Ketone

PubMed: Raspberry ketone regulates expression of adiponectin and increases fatty acid oxidation in 3T3-L1 adipocytes and C57BL/6 mice

PubMed: Antioxidant activity and polyphenol content of red raspberry extracts

PubMed: Topical application of raspberry extract improves skin cell function and elasticity via IGF-I upregulation

NIH National Center for Complementary and Integrative Health: Dietary Supplements for Weight Loss

Concise review of efficacy and safety for weight-loss supplements including raspberry ketone.

Examine.com: Raspberry Ketone

Scientific summary including human and animal evidence, safety, and effectiveness.

Laatst bijgewerkt: 1 februari 2026

This information is for educational purposes only and does not replace medical advice.