Vitexin is a plant-derived flavone glycoside found in sources like hawthorn, passionflower, and bamboo leaves. It is studied for antioxidant and anti-inflammatory activity, with much evidence coming from preclinical research.

What are the potential benefits of vitexin?

Vitexin is being explored for cardioprotective support, antioxidant effects, and inflammation modulation. Human evidence is limited, so benefits are not yet well established for clinical use.

What is a typical vitexin dosage?

Supplement amounts commonly fall around 30–100 mg per day. The best dose can vary by product and purpose, so follow label directions and consider medical guidance.

Is vitexin safe and are there side effects?

Safety data in humans is limited, and side effects are not well characterized. People who are pregnant or breastfeeding, have medical conditions, or take medications should consult a clinician before use.

What foods or herbs contain vitexin?

Vitexin occurs naturally in plants such as hawthorn, passionflower, and bamboo leaves. The amount can vary widely by species, growing conditions, and preparation method.

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Vitexin

Limited research available·3/10

A higher score indicates better study conditions, but not necessarily effectiveness.

Vitexin is a plant-derived flavone glycoside studied for its antioxidant, anti-inflammatory, and cardioprotective properties.

Anti-inflammatory Cardiovascular Support Antioxidant

dose range

30–100 mg

once daily

Consumption

Take with food to potentially improve absorption, preferably as part of a standardized plant extract.

Not fat-soluble.

Best time

Any time of day; consistency may be more important than timing.

Description

Vitexin is a naturally occurring flavone glycoside found in hawthorn, passionflower, and bamboo leaves. Used in traditional and modern supplements, it is being explored for heart health and inflammation reduction, although most research is preclinical.

benefits

Main effects with level of evidence

Limited

Note on evidence

Most evidence comes from cell or animal studies, with a lack of robust human clinical trials.

Cardioprotective support

Limited

Vitexin may reduce cardiac injury and improve myocardial function, potentially benefiting heart health.

Particularly relevant for: Adults seeking cardiovascular support

S1 · PubMed: Vitexin attenuates cardiac remodeling in ischemia-reperfusion injury S6 · Nutrients: Review of vitexin pharmacological activities

Anti-inflammatory effects

Limited

Vitexin may help reduce inflammation by inhibiting pro-inflammatory pathways and cytokines.

Particularly relevant for: Adults with inflammatory concerns

S2 · PubMed: Anti-inflammatory effects of vitexin in acute lung injury S6 · Nutrients: Review of vitexin pharmacological activities

Antioxidant activity

Limited

Vitexin acts as an antioxidant, scavenging free radicals and enhancing endogenous defenses.

Particularly relevant for: Adults seeking antioxidant support

S3 · PubMed: Antioxidant effects of vitexin in neurodegenerative disease model S6 · Nutrients: Review of vitexin pharmacological activities

Safety & Information

Important safety information & known risks

For educational purposes only • not medical advice

In studies, vitexin has a good safety profile at typical doses, but human data are limited.

warning notices

Rarely, gastrointestinal discomfort (nausea, mild irritation) may occur.
Pregnancy and breastfeeding: safety not established.
May increase bleeding risk for certain individuals.
Avoid use during pregnancy or breastfeeding due to insufficient safety data.
Consult a healthcare provider before use if you are taking anticoagulant or antiplatelet medications.
Monitor for bleeding risk if you have a bleeding disorder or are using blood-thinning medication.

Known interactions with medications

anticoagulant or antiplatelet medications (risk of bleeding)

Contraindications / special precautions

pregnancy
breastfeeding
bleeding disorders

interactions

Important interactions between active ingredient ↔ supplement / medication / food

Vitexin may affect blood clotting and interact with anticoagulant medications.

Vitexin may enhance effects of blood thinners.

drug · anticoagulant or antiplatelet medications

CautionLimited

Why

Due to its effects on platelet aggregation and blood parameters, vitexin might increase bleeding risk when combined with anticoagulant or antiplatelet drugs.

recommendation

Consult your healthcare provider before use; monitor for signs of increased bleeding.

S4 · Examine.com: Vitexin Overview S6 · Nutrients: Review of vitexin pharmacological activities

mechanisms of action

Brief explanations of how it works

Antioxidant defense enhancement

Vitexin enhances endogenous antioxidant enzymes like superoxide dismutase, reducing oxidative damage and lipid peroxidation.

S3 · PubMed: Antioxidant effects of vitexin in neurodegenerative disease model S6 · Nutrients: Review of vitexin pharmacological activities

Anti-inflammatory pathway modulation

Vitexin inhibits NF-κB and COX-2 signaling, leading to lower production of pro-inflammatory cytokines.

S2 · PubMed: Anti-inflammatory effects of vitexin in acute lung injury S6 · Nutrients: Review of vitexin pharmacological activities

Cardioprotective signaling modulation

Vitexin modulates MAPK and related pathways, reducing cell death and damage in cardiac tissue during ischemia-reperfusion.

S1 · PubMed: Vitexin attenuates cardiac remodeling in ischemia-reperfusion injury S6 · Nutrients: Review of vitexin pharmacological activities

Sources & References

Primary literature and reviews on which these statements are based

6 sources

PubMed: Vitexin attenuates cardiac remodeling in ischemia-reperfusion injury

PubMed: Anti-inflammatory effects of vitexin in acute lung injury

PubMed: Antioxidant effects of vitexin in neurodegenerative disease model

Examine.com: Vitexin Overview

NIH: ChemIDplus - Vitexin

Nutrients: Review of vitexin pharmacological activities

Laatst bijgewerkt: 6 februari 2026

This information is for educational purposes only and does not replace medical advice.