Agnuside
Agnuside is a key active compound in chasteberry (Vitex agnus-castus), used primarily for hormone balance and women’s reproductive health.
Agnuside is an iridoid glycoside considered a major active component of Vitex agnus-castus (chasteberry). It is thought to contribute to the traditional use of the plant for female hormone regulation and cyclic discomfort.
Most clinical evidence focuses on whole Chasteberry extract, not isolated agnuside; agnuside is considered one of its primary actives, but human trials on agnuside alone are lacking.
Supports menstrual cycle comfort
ModerateAgnuside-containing chasteberry extract may reduce symptoms of premenstrual syndrome (PMS), such as breast tenderness and mood swings.
May promote hormonal balance in reproductive-age women
LimitedAgnuside in chasteberry is linked to restored cycle regularity and support for female fertility, mainly through effects on prolactin levels.
Potential relief of menopausal symptoms
LimitedPreliminary data suggest chasteberry, and thus agnuside, may help manage mild menopausal discomforts, but robust evidence is lacking.
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