Alliin is a stable sulfur-containing compound naturally present in fresh garlic (Allium sativum). When garlic is crushed or chewed, alliin can be converted into allicin.

How does alliin differ from allicin?

Alliin is the precursor compound found in intact garlic, while allicin is formed after garlic is damaged (e.g., chopped or crushed). Allicin is more reactive and contributes to garlic’s characteristic odor.

What are the potential health benefits of alliin?

Alliin and garlic preparations containing it are associated with cardiovascular support, antioxidant activity, immune modulation, and anti-inflammatory effects. Benefits can vary depending on the garlic product and how it is processed.

What is a typical alliin dosage?

A commonly used supplemental range is about 300–1200 mg per day, depending on the product and formulation. Follow the label directions and consider medical advice if you have health conditions.

Is alliin safe, and who should be cautious?

Alliin from garlic foods and supplements is generally well tolerated, but it may cause digestive upset in some people. Use caution if you take blood-thinning medications, have bleeding disorders, or are preparing for surgery.

Bilimsel destekli 313 besin

3251 kaynak incelendi

Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Besin bul

Popüler seçimler

Eicosapentaenoic acid (EPA)Vitamin D3 Docosahexaenoic acid (DHA)Zinc (Bisglycinate)

Toplam 313 besin

Vitamin B

Vitamin B1 (Thiamine)

Vitamin B2 (Riboflavin)

Vitamin B3 (Niacin)

Vitamin B5 (Pantothenic Acid)

Vitamin B6 (Pyridoxine)

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin B12 (Methylcobalamin)

Vitamin B12 (Cobalamin)

Vitamin A & Carotenoids

Vitamin C

Vitamin D

Vitamin E

Vitamin K

Vitaminoids

Trimethylglycine (Betaine)

NMN (Nicotinamide Mononucleotide)

Pyrroloquinoline Quinone (PQQ)

D-Chiro-Inositol

Coenzym Q10 (Ubiquinone)

Betaine HCL

Nicotinamide Riboside

Vitamin B8 (Myo-Inositol)

Choline

Citicoline (CDP-Choline)

Coenzyme Q10 (Ubiquinol)

Calcium

Calcium Alpha-Ketoglutarate

Magnesium

Magnesium Bisglycinate

Magnesium L-Threonate

Trace Minerals

Copper (Bisglycinate)

Chromium Picolinate

Manganese (Bisglycinate)

Zinc

Pentadecanoic Acid (C15:0)

Phosphatidylserine

R-Alpha Lipoic Acid

Black Cumin Oil

Extra Virgin Olive Oil

Ceratiq wheat oil extract

Phospholipids

Algae Oil

Fish Oil

Conjugated Linoleic Acid

Gamma-Aminobutyric Acid

Alpha-Linolenic Acid

Gamma-Linolenic Acid

Omega-3

Docosapentaenoic acid (DPA)

Eicosapentaenoic acid (EPA)

Docosahexaenoic acid (DHA)

AminoMar

Acetyl-L-Carnitine

PABA (para-aminobenzoic acid)

Essential Amino Acids

Conditionally Essential Amino Acids

L-Theanine

Non-Essential Amino Acids

Beta-Alanine

L-Cysteine Hydrochloride

Amino Acid Derivative

Taurine

Creatine (Hydrochloride)

L-Arginine Alpha-Ketoglutarate

Creatine (Monohydrate)

Akkermansia muciniphila

Lactobacillus Reuteri

Probiotics

Bifidobacterium longum BB536

Prebiotics

Stinging Nettle Extract

Pomegranate Polyphenols

Red Beet Extract

Pine Extract (Pycnogenol)

Oligomeric Proanthocyanidins (OPC)

Ashwagandha Root Extract

Methylsulfonylmethane (MSM)

Citrus Sinensis Extract

Horsetail Stem Extract

Flax Seed Extract

Sulforaphane Glucosinolate

Garlic Extract

Black Pepper

Apricot Kernel Extract

Lovage

Spiny Rest Harrow Root Extract

Juniper Berry Extract

Bearberry Leaf Extract

White Kidney Bean Extract

Lady’s Mantle Extract

Bitter Orange Extract

St. John’s Wort Extract

Japanese Knotweed Extract

Hydroxytyrosol/tyrosol

Olive extract

Sesame seed lignan extract

Broccoli Sprout Extract

Cranberry Extract

Flavon Glycosides

Gentian Root Extract

Griffonia simplicifolia Extract

Ajuga Turkestanica Extract

Amaranthus Leaf Extract

Banaba Extract

Boswellia Extract

Capsaicin

Cayenne Pepper Extract

Celery Extract

Ceylon Cinnamon Extract

Chamomile Extract

Charantin

Chinese Goldthread Root Extract

Citrus Aurantium Extract

Cocoa Extract

Cyanotis Arachnoidea Extract

Fadogia Agrestis Extract

Garcinia Cambogia Extract

Goldenrod Extract

Green Tea Extract

Guarana Extract

Horse Chestnut Extract

Grapefruit Seed Extract

Grape Vine Leaf Extract

Green Tea Polyphenols

Epigallocatechin Gallate (EGCG)

Adaptogens

Cordyceps sinensis extract

Ginsenoside

Lion's Mane (Hericium erinaceus)

Ginseng Extract

Cat's Claw (Uncaria tomentosa)

Arjuna (Terminalia arjuna)

Tribulus Terrestris Extract

Rhodiola rosea

Panax Ginseng Extract

Mushrooms

Reishi Extract

Astragalus Polysaccharides

Hyaluronic Acid

Glucosamine Sulfate

Chondroitin Sulfate

Glucosamine Sulphate 2KCL

Alliin

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Alliin is a sulfur-containing compound found in garlic, associated with cardiovascular, antioxidant, and immune benefits.

Anti-inflammatory Cardiovascular Support Antioxidant Immune Booster

Doz aralığı

300–1200 mg

Taken once or twice daily with meals.

Gelir

Use standardized garlic extracts or supplements containing quantified alliin content for consistent dosing; take with food to improve gastrointestinal tolerance.

Yağda çözünmez.

En iyi zaman

Generally taken at any time of day, often with meals.

Açıklama

Alliin is the primary stable sulfur compound in fresh garlic (Allium sativum), converted to allicin when garlic is crushed or chewed. It is credited with many health-supporting effects commonly attributed to garlic supplements and foods.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Evidence for cardiovascular and anti-inflammatory benefits is strongest for garlic extracts, which contain alliin; specific effects from isolated alliin require more human studies.

Supports cardiovascular health

Moderate

Supplementation with garlic extracts containing alliin may help moderately lower blood pressure and cholesterol, contributing to healthier cardiovascular function.

Özellikle ilgili olduğu kişiler: Adults with mild hypertension · Adults seeking cardiovascular support

S1 · NIH Office of Dietary Supplements: Garlic Fact Sheet S4 · Banerjee, S.K., Maulik, S.K. (2002). Effect of garlic on cardiovascular disorders: a review. Nutrition Journal, 1(4).S5 · Ried, K. (2016). Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: An updated meta-analysis and review. Journal of Nutrition, 146(2), 389S–396S.

Antioxidant properties

Moderate

Alliin and its derivatives contribute to garlic's antioxidant effects, helping protect cells from oxidative damage.

Özellikle ilgili olduğu kişiler: General population · Those seeking antioxidant support

S3 · Majewski, M. (2014). Allium sativum: Facts and myths regarding human health. The Journal of Nutrition, 146(2), 271S-273S.S6 · Ernst, E. (2000). Garlic: a review of efficacy and safety. Phytomedicine, 7(4), 323-330.

Immune system modulation

Limited

Alliin and garlic extracts may enhance certain aspects of immune function, potentially supporting resistance to some infections.

Özellikle ilgili olduğu kişiler: Individuals looking to boost immune function

S1 · NIH Office of Dietary Supplements: Garlic Fact Sheet S5 · Ried, K. (2016). Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: An updated meta-analysis and review. Journal of Nutrition, 146(2), 389S–396S.

Anti-inflammatory effects

Limited

Alliin may inhibit pro-inflammatory pathways, contributing to overall anti-inflammatory action in the body.

Özellikle ilgili olduğu kişiler: Adults seeking anti-inflammatory support

S3 · Majewski, M. (2014). Allium sativum: Facts and myths regarding human health. The Journal of Nutrition, 146(2), 271S-273S.S4 · Banerjee, S.K., Maulik, S.K. (2002). Effect of garlic on cardiovascular disorders: a review. Nutrition Journal, 1(4).

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally safe in dietary amounts, but potential for increased bleeding risk exists, especially with high doses or specific medications.

Uyarılar

May cause gastrointestinal upset in some individuals, particularly at higher doses.
High doses of garlic/alliin supplements may increase risk of bleeding, especially if combined with anticoagulant or antiplatelet drugs.
Allergic reactions, though rare, can occur.
Avoid high doses of garlic or alliin supplements if you have a bleeding disorder or are taking anticoagulant or antiplatelet medications due to increased risk of bleeding.
Do not use garlic-derived supplements, including alliin, prior to surgery unless approved by a healthcare provider.
People with known allergy to garlic should avoid alliin supplements.

İlaçlarla bilinen etkileşimler

Increased risk of bleeding with anticoagulants and antiplatelet medications.

Kontrendikasyonlar / özel dikkat gerektiren gruplar

Bleeding disorders
Allergy to garlic

etkileşimler

Etkin madde ↔ takviye / ilaç / gıda arasındaki önemli etkileşimler

Alliin may interact with medications affecting blood clotting and amplify effects of anticoagulant drugs.

May increase risk of bleeding with anticoagulants.

drug · warfarin

CautionModerate

Neden

Garlic-derived compounds may enhance the antiplatelet/anticoagulant effects of drugs like warfarin, increasing bleeding risk.

Öneri

Use alliin supplements only under medical supervision if you are taking anticoagulants.

S6 · Ernst, E. (2000). Garlic: a review of efficacy and safety. Phytomedicine, 7(4), 323-330.S7 · Rahman, K. (2007). Effects of garlic on platelet biochemistry and physiology. Molecular Nutrition & Food Research, 51(11), 1335-1344.

May enhance effects of antiplatelet drugs like aspirin.

nutrient · Aspirin

CautionModerateAspirin

Neden

Alliin and garlic compounds can reduce platelet aggregation, potentially enhancing bleeding risk with antiplatelet agents.

Öneri

Monitor for signs of increased bleeding if combining with aspirin or similar drugs.

Etki mekanizmaları

Nasıl çalıştığına dair kısa açıklamalar

Alliin conversion to allicin

When garlic is crushed or chewed, alliin is converted by the enzyme alliinase into allicin, which has biological activity linked to many health effects of garlic.

S3 · Majewski, M. (2014). Allium sativum: Facts and myths regarding human health. The Journal of Nutrition, 146(2), 271S-273S.