What is Dimethyl Glycine (DMG)?

Dimethyl Glycine (DMG), also called dimethylglycine, is a glycine derivative produced in small amounts in the body and found in some foods. It is sold as a dietary supplement.

What are the potential benefits of DMG?

DMG is marketed for energy, immune function, and exercise performance. Human clinical evidence is limited, and benefits are not consistently confirmed.

What is a typical DMG dosage?

Common supplemental amounts are about 100–500 mg per day. Follow product directions and consider discussing dosing with a clinician, especially if you have medical conditions.

Is DMG safe and what are possible side effects?

DMG is generally well tolerated for many people at typical supplement doses, but side effects can occur. Stop use and seek medical advice if you develop concerning symptoms or reactions.

Does DMG help with cognitive function or autism?

DMG has been studied as an adjunct in conditions such as autism spectrum disorder, but controlled evidence has not established clear cognitive benefits. It should not replace standard care.

Bilimsel destekli 313 besin

3251 kaynak incelendi

Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Besin bul

Popüler seçimler

Eicosapentaenoic acid (EPA)Vitamin D3 Docosahexaenoic acid (DHA)Zinc (Bisglycinate)

Toplam 313 besin

Vitamin B

Vitamin B1 (Thiamine)

Vitamin B2 (Riboflavin)

Vitamin B3 (Niacin)

Vitamin B5 (Pantothenic Acid)

Vitamin B6 (Pyridoxine)

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin B12 (Methylcobalamin)

Vitamin B12 (Cobalamin)

Vitamin A & Carotenoids

Vitamin C

Vitamin D

Vitamin E

Vitamin K

Vitaminoids

Trimethylglycine (Betaine)

NMN (Nicotinamide Mononucleotide)

Pyrroloquinoline Quinone (PQQ)

D-Chiro-Inositol

Coenzym Q10 (Ubiquinone)

Betaine HCL

Nicotinamide Riboside

Vitamin B8 (Myo-Inositol)

Choline

Citicoline (CDP-Choline)

Coenzyme Q10 (Ubiquinol)

Calcium

Calcium Alpha-Ketoglutarate

Magnesium

Magnesium Bisglycinate

Magnesium L-Threonate

Trace Minerals

Copper (Bisglycinate)

Chromium Picolinate

Manganese (Bisglycinate)

Zinc

Pentadecanoic Acid (C15:0)

Phosphatidylserine

R-Alpha Lipoic Acid

Black Cumin Oil

Extra Virgin Olive Oil

Ceratiq wheat oil extract

Phospholipids

Algae Oil

Fish Oil

Conjugated Linoleic Acid

Gamma-Aminobutyric Acid

Alpha-Linolenic Acid

Gamma-Linolenic Acid

Omega-3

Docosapentaenoic acid (DPA)

Eicosapentaenoic acid (EPA)

Docosahexaenoic acid (DHA)

AminoMar

Acetyl-L-Carnitine

PABA (para-aminobenzoic acid)

Essential Amino Acids

Conditionally Essential Amino Acids

L-Theanine

Non-Essential Amino Acids

Beta-Alanine

L-Cysteine Hydrochloride

Amino Acid Derivative

Taurine

Creatine (Hydrochloride)

L-Arginine Alpha-Ketoglutarate

Creatine (Monohydrate)

Akkermansia muciniphila

Lactobacillus Reuteri

Probiotics

Bifidobacterium longum BB536

Prebiotics

Stinging Nettle Extract

Pomegranate Polyphenols

Red Beet Extract

Pine Extract (Pycnogenol)

Oligomeric Proanthocyanidins (OPC)

Ashwagandha Root Extract

Methylsulfonylmethane (MSM)

Citrus Sinensis Extract

Horsetail Stem Extract

Flax Seed Extract

Sulforaphane Glucosinolate

Garlic Extract

Black Pepper

Apricot Kernel Extract

Lovage

Spiny Rest Harrow Root Extract

Juniper Berry Extract

Bearberry Leaf Extract

White Kidney Bean Extract

Lady’s Mantle Extract

Bitter Orange Extract

St. John’s Wort Extract

Japanese Knotweed Extract

Hydroxytyrosol/tyrosol

Olive extract

Sesame seed lignan extract

Broccoli Sprout Extract

Cranberry Extract

Flavon Glycosides

Gentian Root Extract

Griffonia simplicifolia Extract

Ajuga Turkestanica Extract

Amaranthus Leaf Extract

Banaba Extract

Boswellia Extract

Capsaicin

Cayenne Pepper Extract

Celery Extract

Ceylon Cinnamon Extract

Chamomile Extract

Charantin

Chinese Goldthread Root Extract

Citrus Aurantium Extract

Cocoa Extract

Cyanotis Arachnoidea Extract

Fadogia Agrestis Extract

Garcinia Cambogia Extract

Goldenrod Extract

Green Tea Extract

Guarana Extract

Horse Chestnut Extract

Grapefruit Seed Extract

Grape Vine Leaf Extract

Green Tea Polyphenols

Epigallocatechin Gallate (EGCG)

Adaptogens

Cordyceps sinensis extract

Ginsenoside

Lion's Mane (Hericium erinaceus)

Ginseng Extract

Cat's Claw (Uncaria tomentosa)

Arjuna (Terminalia arjuna)

Tribulus Terrestris Extract

Rhodiola rosea

Panax Ginseng Extract

Mushrooms

Reishi Extract

Astragalus Polysaccharides

Hyaluronic Acid

Glucosamine Sulfate

Chondroitin Sulfate

Glucosamine Sulphate 2KCL

Dimethyl Glycine
(DMG)

Sınırlı araştırma durumu·3/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Dimethylglycine (DMG) is a naturally occurring compound marketed as a dietary supplement for energy, immune function, and exercise performance, with limited human clinical evidence.

Cognitive Enhancement Exercise Performance Immune Booster Liver Health Energy Support

Doz aralığı

100–500 mg

1–2 divided doses per day

Gelir

DMG can be taken with or without food.

Yağda çözünmez.

En iyi zaman

No strict timing required; take with or without meals.

Açıklama

Dimethylglycine (DMG) is a derivative of the amino acid glycine, produced in small amounts in the human body and found in certain foods. It is promoted to support energy, immunity, cognitive function, and athletic performance, though robust clinical evidence is limited.

Avantajlar

Kanıt derecesi ile ana etkiler

Limited

Kanıtla ilgili not

While DMG is widely marketed for several health benefits, available research in humans is scarce, with most effects observed in preliminary, small-scale, or animal studies.

Supports immune response (limited evidence)

Limited

Preliminary studies suggest that DMG supplementation may support aspects of immune function by enhancing antibody responses, particularly under physical stress, but robust evidence in humans is lacking.

Özellikle ilgili olduğu kişiler: athletes · individuals seeking immune support

examine_dmg · Examine.com: Dimethylglycine (DMG)pmid_15330136 · Efficiency of dimethylglycine in increasing oxygen utilization and immune response

May improve exercise performance (limited evidence)

Limited

Some animal studies and a few small human trials suggest DMG could aid oxygen utilization during exercise, though consistent, clinically meaningful benefits in athletes have not been confirmed.

Özellikle ilgili olduğu kişiler: athletes · active individuals

examine_dmg · Examine.com: Dimethylglycine (DMG)pmid_15330136 · Efficiency of dimethylglycine in increasing oxygen utilization and immune response

Potential support for cognitive function (theoretical)

Theoretical

DMG was previously investigated as an adjunct in conditions such as autism spectrum disorder, but quality controlled studies have not established cognitive benefits.

Özellikle ilgili olduğu kişiler: individuals seeking cognitive enhancement

cochrane_autismspectrum · Cochrane Review: DMG in autism spectrum disorders examine_dmg · Examine.com: Dimethylglycine (DMG)

Potential role in mitochondrial and liver health (theoretical)

Theoretical

DMG is involved in methylation and mitochondrial activity, and it is used for liver health in some contexts, but clinical trials are lacking.

Özellikle ilgili olduğu kişiler: individuals with mitochondrial disorders · those interested in liver support

lpi_dmg · Linus Pauling Institute: DMG Research pmid_16566782 · Dimethylglycine in mitochondrial diseases: review

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

DMG supplementation is generally well-tolerated at typical doses, but safety has not been thoroughly established, especially in higher risk groups.

Uyarılar

Use only under medical supervision if you have a seizure disorder or take psychiatric medications.
Safety has not been established in pregnant or breastfeeding women.
Adverse effects are rare but may include irritability or overstimulation.
Avoid DMG supplements if you have unmanaged epilepsy unless used under clinical supervision.
Use caution and consult a healthcare provider if pregnant, breastfeeding, or taking medications for psychiatric or seizure disorders.

İlaçlarla bilinen etkileşimler

Possible interaction with antiepileptic drugs.

Kontrendikasyonlar / özel dikkat gerektiren gruplar

History of epilepsy or seizure disorder without clinician oversight.

etkileşimler

Etkin madde ↔ takviye / ilaç / gıda arasındaki önemli etkileşimler

DMG has limited known supplement or drug interactions, but may theoretically affect medications relevant to seizure disorders and methylation pathways.

Use caution with antiepileptic drugs

drug · Antiepileptic drugs

CautionLimited

Neden

DMG has been reported anecdotally and in case reports to potentially lower seizure threshold in some individuals.

Öneri

Consult a healthcare provider if taking antiepileptics or with seizure history before using DMG.

examine_dmg · Examine.com: Dimethylglycine (DMG)ods_dmg · NIH Office of Dietary Supplements: Dimethylglycine

Etki mekanizmaları

Nasıl çalıştığına dair kısa açıklamalar

Methyl donor in one-carbon metabolism

DMG acts as a methyl group donor, influencing homocysteine metabolism and supporting methylation pathways involved in DNA and neurotransmitter synthesis.

lpi_dmg · Linus Pauling Institute: DMG Research examine_dmg · Examine.com: Dimethylglycine (DMG)