Pentadecanoic Acid
(C15:0)
Odd-chain saturated fatty acid found in dairy and certain animal products, associated with metabolic, liver, and cardiovascular benefits based on emerging evidence.
Pentadecanoic acid (C15:0) is an odd-chain saturated fatty acid found in dairy fat, ruminant meats, and some fish and plants. It has garnered attention as a potential essential fatty acid with possible roles in supporting metabolic and cardiovascular health.
Preliminary human and animal studies show potential cardiometabolic and anti-inflammatory benefits, but larger, long-term clinical trials are needed to confirm efficacy and safety.
Supports Cardiometabolic Health
LimitedHigher circulating levels of C15:0 have been associated with reduced risks of cardiovascular disease, type 2 diabetes, and metabolic syndrome; supplementation may modestly lower cholesterol, triglycerides, and glucose in preliminary studies.
Reduces Inflammation
LimitedIn vitro and early clinical evidence indicate C15:0 may lower inflammatory cytokines, such as MCP-1 and IL-6, suggesting a role in managing chronic inflammation.
Promotes Liver Health
LimitedA 12-week clinical trial showed C15:0 supplementation increased circulating levels and reduced liver enzymes (ALT, AST) in individuals with elevated baseline levels, implying liver protective effects.
Potential Anti-Cancer Effects
TheoreticalPreliminary cell studies suggest pentadecanoic acid may suppress breast cancer stem-like cell growth, but human data are lacking.
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