D-Chiro-Inositol
D-Chiro-Inositol is a naturally occurring inositol isomer used as a supplement for metabolic and reproductive health, especially in PCOS and insulin resistance.
D-Chiro-Inositol (DCI) is a form of inositol involved in insulin signaling and glucose metabolism. It is less abundant than myo-inositol in the body but plays a distinct role in glycogen synthesis and hormonal regulation. DCI supplements are primarily explored for PCOS, type 2 diabetes, and metabolic syndrome, often combined with myo-inositol for best results.
Clinical studies support DCI's role in PCOS and metabolic syndrome, but more large, long-term trials are needed.
Supports insulin sensitivity and ovulation in PCOS
ModerateDCI supplementation improves insulin sensitivity, lowers testosterone, and supports ovulation in women with PCOS, especially when combined with myo-inositol.
Improves glycemic control in type 2 diabetes
LimitedD-Chiro-Inositol, often combined with myo-inositol, may lower fasting blood glucose and HbA1c, supporting overall metabolic health in people with type 2 diabetes.
May improve lipid profile and reduce blood pressure in metabolic syndrome
LimitedDCI may reduce triglycerides and blood pressure, offering cardiovascular support in metabolic syndrome according to preliminary evidence.
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