What does vitamin B5 (pantothenic acid) do in the body?

Vitamin B5 is needed to make coenzyme A, which helps convert carbohydrates, fats, and proteins into energy. It also supports synthesis of fatty acids and certain hormones and neurotransmitters.

What are common food sources of vitamin B5?

Vitamin B5 is widely found in many foods, including meats, eggs, dairy, legumes, whole grains, and some vegetables. Because it is broadly available, deficiency is uncommon.

What are signs of vitamin B5 deficiency?

Deficiency is rare but can contribute to general symptoms such as fatigue and malaise. Symptoms are often nonspecific and may overlap with other nutrient deficiencies.

How much vitamin B5 should I take as a supplement?

Typical supplemental amounts range from about 5 mg to 200 mg per day, depending on the product and goal. Higher-dose use should be discussed with a clinician, especially when using specialized forms like pantethine.

Is pantethine the same as pantothenic acid for cholesterol support?

Pantethine is a related form of vitamin B5 that is commonly used in supplements aimed at supporting blood lipid levels. It is not identical to pantothenic acid, and dosing and effects may differ.

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Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Vitamin B5
(Pantothenic Acid)

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Essential B vitamin involved in energy and fat metabolism, broadly found in foods and typically only supplemented for specific reasons.

Stress Relief Essential Nutrient Skin Health Cholesterol Management Anxiety Relief Hormone Balance

Doz aralığı

5–200 mg

Single or divided doses with food

Gelir

Best taken with food to support absorption; included in most B-complex and multivitamin supplements.

Yağda çözünmez.

En iyi zaman

Morning or with meals is common. No specific timing is critical due to its water solubility.

Açıklama

Vitamin B5 (pantothenic acid) is a water-soluble B vitamin crucial for creating coenzyme A, a molecule necessary for turning food into cellular energy and synthesizing fats, hormones, and neurotransmitters. Deficiency is rare due to its wide presence in food.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Evidence is strongest for deficiency syndromes and for the lipid-lowering effects of pantethine, a derivative used in clinical trials, while general supplementation is less commonly needed.

Supports cellular energy metabolism

Strong

B5 is essential for the synthesis of coenzyme A, which helps convert carbohydrates, fats, and proteins into usable cellular energy (ATP). Deficiency leads to fatigue and malaise.

Özellikle ilgili olduğu kişiler: General population · Athletic individuals

source1 · NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet source2 · Healthline: Vitamin B5 (Pantothenic Acid)source3 · VerywellHealth: Pantothenic Acid Benefits and Nutrition

Helps manage cholesterol and triglycerides (pantethine form)

Moderate

High-dose pantethine supplementation has been shown to reduce triglycerides and modestly improve cholesterol profile in individuals with elevated blood lipids.

Özellikle ilgili olduğu kişiler: Adults with high cholesterol or triglycerides

source6 · Cochrane Review: Pantethine for cholesterol and triglycerides source1 · NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet

Promotes healthy skin and wound healing

Limited

Pantothenic acid is required for fatty acid synthesis, supporting healthy skin barrier function; deficiency can lead to dermatitis, and some studies suggest benefit for acne.

Özellikle ilgili olduğu kişiler: Individuals with skin concerns

source5 · Mount Sinai: Pantothenic Acid (Vitamin B5)source7 · Examine.com: Pantothenic Acid source2 · Healthline: Vitamin B5 (Pantothenic Acid)

Supports adrenal hormone synthesis and stress response

Limited

B5 is involved in steroid hormone production in the adrenal glands, which are key to the body's response to stress; however, direct benefits for stress reduction are not well established.

Özellikle ilgili olduğu kişiler: People under chronic stress

source1 · NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet source3 · VerywellHealth: Pantothenic Acid Benefits and Nutrition

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Pantothenic acid is very safe at typical dietary levels; high doses may cause mild GI side effects.

Uyarılar

No established toxicity; overdose is rare due to efficient excretion.
High doses (over 200 mg/day) can cause diarrhea or stomach upset in some individuals.
Deficiency is extremely rare outside of severe malnutrition.
Avoid high-dose supplementation (>200 mg/day) unless supervised due to potential for gastrointestinal upset.
People with active diarrhea should avoid high-dose pantothenic acid supplements as they may worsen symptoms.

Kontrendikasyonlar / özel dikkat gerektiren gruplar

Active diarrhea (avoid high-dose B5).

Etki mekanizmaları

Nasıl çalıştığına dair kısa açıklamalar

Cofactor in energy metabolism via coenzyme A

Pantothenic acid forms part of coenzyme A, which is essential for Krebs cycle activity and fatty acid oxidation, enabling ATP generation from macronutrients.

source1 · NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet source3 · VerywellHealth: Pantothenic Acid Benefits and Nutrition

Synthesis of cholesterol and steroid hormones

B5-dependent coenzyme A is required for synthesizing cholesterol and adrenal hormones, supporting stress responses and hormone production.

source1 · NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet source4 · WebMD: Pantothenic Acid (Vitamin B5)

Fatty acid synthesis and skin health

Essential for synthesizing long-chain fatty acids, supporting skin barrier maintenance and repair; deficiency disrupts skin and hair integrity.

source5 · Mount Sinai: Pantothenic Acid (Vitamin B5)source7 · Examine.com: Pantothenic Acid

Kaynaklar ve Referanslar

Bu ifadelerin dayandığı birincil kaynaklar ve incelemeler

7 sources

source1

NIH Office of Dietary Supplements: Pantothenic Acid Fact Sheet

source2

Healthline: Vitamin B5 (Pantothenic Acid)

source3

VerywellHealth: Pantothenic Acid Benefits and Nutrition

source4

WebMD: Pantothenic Acid (Vitamin B5)

source5

Mount Sinai: Pantothenic Acid (Vitamin B5)

source6

Cochrane Review: Pantethine for cholesterol and triglycerides

Pantethine clinical trial data

source7

Examine.com: Pantothenic Acid

Son güncelleme: 13 Şubat 2026

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Tüm besinler

Vitamin B5
(Pantothenic Acid)

Açıklama

Avantajlar

Supports cellular energy metabolism

Helps manage cholesterol and triglycerides (pantethine form)

Promotes healthy skin and wound healing

Supports adrenal hormone synthesis and stress response

Güvenlik ve Uyarılar

Etki mekanizmaları

Cofactor in energy metabolism via coenzyme A

Synthesis of cholesterol and steroid hormones

Fatty acid synthesis and skin health

Kaynaklar ve Referanslar

Vitamins & Vitaminoids

Diğer kategoriler

Güvenlik ve Uyarılar

Etki mekanizmaları

Cofactor in energy metabolism via coenzyme A

Synthesis of cholesterol and steroid hormones

Fatty acid synthesis and skin health

Kaynaklar ve Referanslar

Vitamin B5(Pantothenic Acid)

Açıklama

Avantajlar

Supports cellular energy metabolism

Helps manage cholesterol and triglycerides (pantethine form)

Promotes healthy skin and wound healing

Supports adrenal hormone synthesis and stress response

Güvenlik ve Uyarılar

Etki mekanizmaları

Cofactor in energy metabolism via coenzyme A

Synthesis of cholesterol and steroid hormones

Fatty acid synthesis and skin health

Kaynaklar ve Referanslar

Vitamins & Vitaminoids

Diğer kategoriler

Güvenlik ve Uyarılar

Etki mekanizmaları

Cofactor in energy metabolism via coenzyme A

Synthesis of cholesterol and steroid hormones

Fatty acid synthesis and skin health

Kaynaklar ve Referanslar

Vitamin B5
(Pantothenic Acid)