Vitamin B5
(Pantothenic Acid)
Essential B vitamin involved in energy and fat metabolism, broadly found in foods and typically only supplemented for specific reasons.
Vitamin B5 (pantothenic acid) is a water-soluble B vitamin crucial for creating coenzyme A, a molecule necessary for turning food into cellular energy and synthesizing fats, hormones, and neurotransmitters. Deficiency is rare due to its wide presence in food.
Evidence is strongest for deficiency syndromes and for the lipid-lowering effects of pantethine, a derivative used in clinical trials, while general supplementation is less commonly needed.
Supports cellular energy metabolism
StrongB5 is essential for the synthesis of coenzyme A, which helps convert carbohydrates, fats, and proteins into usable cellular energy (ATP). Deficiency leads to fatigue and malaise.
Helps manage cholesterol and triglycerides (pantethine form)
ModerateHigh-dose pantethine supplementation has been shown to reduce triglycerides and modestly improve cholesterol profile in individuals with elevated blood lipids.
Promotes healthy skin and wound healing
LimitedPantothenic acid is required for fatty acid synthesis, supporting healthy skin barrier function; deficiency can lead to dermatitis, and some studies suggest benefit for acne.
Supports adrenal hormone synthesis and stress response
LimitedB5 is involved in steroid hormone production in the adrenal glands, which are key to the body's response to stress; however, direct benefits for stress reduction are not well established.
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