What is Fadogia Agrestis Extract?

Fadogia Agrestis Extract comes from the West African shrub Fadogia agrestis. It is commonly marketed for male sexual health and purported testosterone support.

Does Fadogia Agrestis Extract increase testosterone in humans?

There is little to no direct human evidence that it increases testosterone. Most support for this claim comes from animal studies, which may not translate to people.

What are the potential benefits of Fadogia Agrestis Extract?

Animal studies suggest possible effects on testosterone-related markers and sexual behavior, and some report analgesic or anti-inflammatory activity. Human relevance and real-world benefits remain uncertain.

What is a typical dosage range for Fadogia Agrestis Extract?

Common supplemental amounts are often listed around 100–600 mg per day. Optimal dosing is not established due to limited human research.

Is Fadogia Agrestis Extract safe?

Safety in humans is not well established, and product quality can vary between brands. People with medical conditions, those taking medications, or those who are pregnant or breastfeeding should consult a clinician before use.

313 wetenschappelijk onderbouwde voedingsstoffen

3251 bronnen geraadpleegd

Informatie ingedeeld naar bewijs

Verken op doel of categorie

Voedingsstof vinden

Populaire keuzes

Eicosapentaenoic acid (EPA)Vitamin D3 Docosahexaenoic acid (DHA)Zinc (Bisglycinate)

313 voedingsstoffen totaal

Vitamin B

Vitamin B1 (Thiamine)

Vitamin B2 (Riboflavin)

Vitamin B3 (Niacin)

Vitamin B5 (Pantothenic Acid)

Vitamin B6 (Pyridoxine)

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin B12 (Methylcobalamin)

Vitamin B12 (Cobalamin)

Vitamin A & Carotenoids

Vitamin C

Vitamin D

Vitamin E

Vitamin K

Vitaminoids

Trimethylglycine (Betaine)

NMN (Nicotinamide Mononucleotide)

Pyrroloquinoline Quinone (PQQ)

D-Chiro-Inositol

Coenzym Q10 (Ubiquinone)

Betaine HCL

Nicotinamide Riboside

Vitamin B8 (Myo-Inositol)

Choline

Citicoline (CDP-Choline)

Coenzyme Q10 (Ubiquinol)

Calcium

Calcium Alpha-Ketoglutarate

Magnesium

Magnesium Bisglycinate

Magnesium L-Threonate

Trace Minerals

Copper (Bisglycinate)

Chromium Picolinate

Manganese (Bisglycinate)

Zinc

Pentadecanoic Acid (C15:0)

Phosphatidylserine

R-Alpha Lipoic Acid

Black Cumin Oil

Extra Virgin Olive Oil

Ceratiq wheat oil extract

Phospholipids

Algae Oil

Fish Oil

Conjugated Linoleic Acid

Gamma-Aminobutyric Acid

Alpha-Linolenic Acid

Gamma-Linolenic Acid

Omega-3

Docosapentaenoic acid (DPA)

Eicosapentaenoic acid (EPA)

Docosahexaenoic acid (DHA)

AminoMar

Acetyl-L-Carnitine

PABA (para-aminobenzoic acid)

Essential Amino Acids

Conditionally Essential Amino Acids

L-Theanine

Non-Essential Amino Acids

Beta-Alanine

L-Cysteine Hydrochloride

Amino Acid Derivative

Taurine

Creatine (Hydrochloride)

L-Arginine Alpha-Ketoglutarate

Creatine (Monohydrate)

Akkermansia muciniphila

Lactobacillus Reuteri

Probiotics

Bifidobacterium longum BB536

Prebiotics

Stinging Nettle Extract

Pomegranate Polyphenols

Red Beet Extract

Pine Extract (Pycnogenol)

Oligomeric Proanthocyanidins (OPC)

Ashwagandha Root Extract

Methylsulfonylmethane (MSM)

Citrus Sinensis Extract

Horsetail Stem Extract

Flax Seed Extract

Sulforaphane Glucosinolate

Garlic Extract

Black Pepper

Apricot Kernel Extract

Lovage

Spiny Rest Harrow Root Extract

Juniper Berry Extract

Bearberry Leaf Extract

White Kidney Bean Extract

Lady’s Mantle Extract

Bitter Orange Extract

St. John’s Wort Extract

Japanese Knotweed Extract

Hydroxytyrosol/tyrosol

Olive extract

Sesame seed lignan extract

Broccoli Sprout Extract

Cranberry Extract

Flavon Glycosides

Gentian Root Extract

Griffonia simplicifolia Extract

Ajuga Turkestanica Extract

Amaranthus Leaf Extract

Banaba Extract

Boswellia Extract

Capsaicin

Cayenne Pepper Extract

Celery Extract

Ceylon Cinnamon Extract

Chamomile Extract

Charantin

Chinese Goldthread Root Extract

Citrus Aurantium Extract

Cocoa Extract

Cyanotis Arachnoidea Extract

Fadogia Agrestis Extract

Garcinia Cambogia Extract

Goldenrod Extract

Green Tea Extract

Guarana Extract

Horse Chestnut Extract

Grapefruit Seed Extract

Grape Vine Leaf Extract

Green Tea Polyphenols

Epigallocatechin Gallate (EGCG)

Adaptogens

Cordyceps sinensis extract

Ginsenoside

Lion's Mane (Hericium erinaceus)

Ginseng Extract

Cat's Claw (Uncaria tomentosa)

Arjuna (Terminalia arjuna)

Tribulus Terrestris Extract

Rhodiola rosea

Panax Ginseng Extract

Mushrooms

Reishi Extract

Astragalus Polysaccharides

Hyaluronic Acid

Glucosamine Sulfate

Chondroitin Sulfate

Glucosamine Sulphate 2KCL

Fadogia Agrestis
Extract

Limited research available·3/10

A higher score indicates better study conditions, but not necessarily effectiveness.

Extract from the Fadogia agrestis shrub, traditionally used for male sexual health and purported testosterone support, but lacking human evidence.

Testosterone Booster Anti-inflammatory Male Fertility Hormone Balance

dose range

100–600 mg

Once daily, in the morning or pre-workout

Consumption

Orally, with or without food.

Not fat-soluble.

Best time

Safety of split vs. single dose not established; consider morning or pre-workout to align with theoretical energy benefits.

Description

Fadogia agrestis is a West African shrub whose extracts are marketed as testosterone boosters and aphrodisiacs. Most claims are based on animal studies, with little to no direct human evidence.

benefits

Main effects with level of evidence

Limited

Note on evidence

Most evidence is restricted to animal and in vitro studies. No quality human RCTs or pharmacokinetic data are available.

Possible Testosterone Support (Animal Data Only)

Limited

Animal studies suggest that Fadogia agrestis may increase serum testosterone, likely via stimulation of luteinizing hormone, but these effects are unproven in humans.

Particularly relevant for: Men seeking hormone support

1 · PubMed – Asian Journal of Andrology 5 · Examine.com

Traditional Aphrodisiac Effects (Animal Data Only)

Limited

Fadogia agrestis has demonstrated increased sexual activity and libido in male rats, echoing its folkloric use as an aphrodisiac; relevance to humans is unknown.

Particularly relevant for: Men seeking sexual performance improvement

2 · PubMed – International Journal of Impotence Research 5 · Examine.com6 · NIH National Center for Complementary and Integrative Health (NCCIH)

Animal Evidence for Analgesic and Anti-Inflammatory Activity

Limited

Some animal studies report reduced pain and inflammation with Fadogia agrestis extracts, potentially due to modulation of inflammatory mediators.

Particularly relevant for: Individuals interested in herbal pain relief

3 · PubMed – Journal of Ethnopharmacology 5 · Examine.com

Safety & Information

Important safety information & known risks

For educational purposes only • not medical advice

Long-term human safety is unknown. Animal toxicity is reported at high doses; liver and kidney function risks require caution.

warning notices

Potential for liver and kidney toxicity observed in animal studies at high dosages.
Not recommended for pregnant or breastfeeding women.
No established human safety data for prolonged use or high doses.
Avoid use in pregnancy or breastfeeding due to insufficient safety data.
Do not use if you have pre-existing liver or kidney disease due to potential toxicity observed in animal studies.
Monitor liver and kidney function during use, particularly if used for more than a few weeks.
Avoid or use only with clinician supervision if using hormone-related medications due to unestablished endocrine effects.

Known interactions with medications

Hormonal agents (testosterone, SERMs, anti-androgens)
Drugs with liver/kidney toxicity risk

Contraindications / special precautions

Pregnancy
Breastfeeding
Liver disease
Kidney disease

interactions

Important interactions between active ingredient ↔ supplement / medication / food

Clinically relevant nutrient or drug interactions are unproven, but theoretical interactions exist based on hormonal activity and animal toxicity data.