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Potentilla
Extract

Moderate study situation·7/10
A higher score indicates better study conditions, but not necessarily effectiveness.

Plant extract with traditional use for diarrhea and inflammation, supported by some clinical and preclinical evidence.

Digestion & Gut HealthAnti-inflammatoryAntioxidantAntidiarrheal
dose range
200–1500 mg
2–3 divided doses daily
Consumption
Take with water, preferably with food to reduce GI irritation. Use standardized extracts for consistent tannin content.
Not fat-soluble.
Best time
Best taken with meals; higher doses may cause GI discomfort.

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Description

Potentilla extract, from plants in the Potentilla genus (notably P. erecta and P. alba), is a herbal remedy traditionally used for gastrointestinal, anti-inflammatory, and antioxidant purposes. Its active polyphenols, especially tannins, give it notable astringent properties.

benefits
Main effects with level of evidence
Moderate
Note on evidence

RCTs, traditional use, and preclinical studies exist, but more high-quality human studies are needed.

Supports gastrointestinal health and relieves diarrhea

Moderate

Potentilla extract (especially tormentil root) has demonstrated effectiveness in reducing duration and severity of acute nonspecific diarrhea, likely due to its high tannin content and astringent properties.

Particularly relevant for: Adults with acute diarrhea · Individuals seeking natural GI support
S1 · Clinical trial on Potentilla for diarrheaS4 · EMA Assessment Report: Tormentil rhizome

Reduces inflammation

Limited

Preclinical data demonstrate that Potentilla extracts inhibit inflammatory cytokines and pathways such as NF-κB, suggesting anti-inflammatory potential, especially for gut and oral mucosal inflammation.

Particularly relevant for: Individuals with inflammatory conditions · People seeking complementary anti-inflammatory support
S2 · Review: Pharmacological effects of Potentilla extractsS4 · EMA Assessment Report: Tormentil rhizome

Provides antioxidant and antimicrobial support

Limited

Potentilla species extracts are rich in polyphenols and flavonoids, providing free radical scavenging and mild antimicrobial activity in vitro.

Particularly relevant for: Those seeking dietary antioxidants
S3 · Study: Antioxidant and antimicrobial activityS4 · EMA Assessment Report: Tormentil rhizome

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This information is for educational purposes only and does not replace medical advice.
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