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Epigallocatechin Gallate
(EGCG)

Moderate study situation·7/10
A higher score indicates better study conditions, but not necessarily effectiveness.

Epigallocatechin gallate (EGCG) is a green tea polyphenol with antioxidant, metabolic, and potential cancer-protective effects.

Anti-inflammatoryCardiovascular SupportCancer-inhibitorAntioxidantWeight Management
dose range
200–800 mg
Divided dose (e.g., 2–3 times per day)
Consumption
Take with water, preferably on an empty stomach or between meals to improve absorption. Do not exceed 800 mg daily unless supervised.
Not fat-soluble.
Best time
Taking on an empty stomach or between meals may increase absorption, but may also raise risk of nausea.

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Description

EGCG is the most abundant catechin in green tea, researched for its strong antioxidant capacity and possible roles in weight management, cardiovascular health, and cancer risk reduction.

benefits
Main effects with level of evidence
Moderate
Note on evidence

Supported by multiple clinical trials and population studies for antioxidant and metabolic effects; evidence for cancer prevention is promising but not conclusive in humans.

Antioxidant and Anti-inflammatory Activity

Strong

EGCG neutralizes free radicals and lowers oxidative stress, reducing inflammation and supporting cellular health.

Particularly relevant for: General adults · People seeking antioxidant support
1 · NIH NCCIH Green Tea Fact Sheet2 · PubMed – Antioxidant and anti-inflammatory effects: Nutr Biochem 2006;17(9):561-85.5 · Examine.com – Epigallocatechin gallate (EGCG) supplement overview

Supports Weight Management and Metabolism

Moderate

Supplemental EGCG can enhance fat oxidation and modestly support weight loss when combined with diet and exercise, especially in overweight individuals.

Particularly relevant for: Individuals concerned with weight management · Metabolic health
3 · PubMed – Fat loss and metabolic effects: Am J Clin Nutr. 2009 Dec;90(6):1558-61.8 · Cochrane Review on Green Tea for weight loss in adults5 · Examine.com – Epigallocatechin gallate (EGCG) supplement overview

Potential Cancer Risk Reduction

Limited

EGCG may help inhibit cancer cell growth and exert protective effects, though clinical evidence in humans remains limited.

Particularly relevant for: Cancer prevention interest groups
4 · PubMed – Cancer prevention potential: J Am Coll Nutr. 2012 Feb;31(1):4-9.5 · Examine.com – Epigallocatechin gallate (EGCG) supplement overview

Cardiovascular Health Support

Moderate

EGCG can modestly improve cholesterol profiles and endothelial function, supporting heart health.

Particularly relevant for: Adults concerned about cardiovascular health
1 · NIH NCCIH Green Tea Fact Sheet5 · Examine.com – Epigallocatechin gallate (EGCG) supplement overview7 · ODS – Dietary Supplements Fact Sheet: Green Tea

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This information is for educational purposes only and does not replace medical advice.
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This website is for educational and informational purposes only and does not constitute medical advice or professional services. The information provided should not be used to diagnose or treat any health problem or disease. Persons requiring medical advice should consult a licensed physician.