What is Gotu Kola Extract?

Gotu Kola Extract is a supplement made from Centella asiatica, a plant used in traditional Asian medicine. It contains triterpenoids such as asiaticoside and madecassoside.

What are the main benefits of Gotu Kola Extract?

It is commonly used for cognitive support, anxiety relief, wound healing and skin repair, and circulation or venous health. Effects can vary by extract type and individual response.

How much Gotu Kola Extract should I take?

Typical supplemental amounts range from about 60 to 450 mg per day. Follow the product label and consider starting at the low end to assess tolerance.

How does Gotu Kola Extract support skin and wound healing?

It may support skin repair by promoting collagen-related processes and tissue regeneration. It is used both orally and in topical formulations depending on the product.

Who should be cautious with Gotu Kola Extract?

People who are pregnant or breastfeeding, have liver disease, or take sedatives or other medications should consult a clinician before use. Stop use and seek advice if you develop unusual symptoms.

Bilimsel destekli 313 besin

3262 kaynak incelendi

Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Gotu Kola
Extract

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Traditional Asian herbal extract used for cognitive support, wound healing, and vascular health.

Anti-inflammatory Cardiovascular Support Tissue Repair Cognitive Enhancement Memory Improvement Antioxidant Skin Health Anxiety Relief

Doz aralığı

60–450 mg

Divided 2–3 times daily.

Gelir

Take with food to enhance absorption and reduce GI side effects.

Yağda çözünmez.

En iyi zaman

Morning and evening (pre-sleep) dosing are typical; some cognitive protocols use a single higher dose.

Açıklama

Gotu Kola Extract (Centella asiatica) is an herbal supplement with a long history in Asian traditional medicine. Modern studies suggest benefits for memory, anxiety, circulation, and skin health, primarily due to its triterpenoid compounds such as asiaticoside and madecassoside.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Several human clinical studies support benefits for cognitive, circulatory, and wound healing outcomes, though larger, longer-term studies are needed.

Cognitive Enhancement

Moderate

Supplementation may improve memory, attention, and overall cognitive performance, particularly in older adults.

Özellikle ilgili olduğu kişiler: Older adults · Individuals seeking cognitive support

2 · PubMed (Cognitive Study)

Anxiety Reduction

Moderate

Shows anxiolytic effects similar to some pharmaceuticals, reducing anxiety symptoms without sedation.

Özellikle ilgili olduğu kişiler: Individuals with mild anxiety

3 · PubMed (Anxiety Study)

Wound Healing and Skin Repair

Moderate

May promote wound closure and skin repair by enhancing collagen synthesis and cellular regeneration.

Özellikle ilgili olduğu kişiler: Individuals with slow-healing wounds · Those seeking skin health support

4 · PubMed (Wound/Ulcer Study)

Supports Circulation and Venous Health

Moderate

May help reduce symptoms of chronic venous insufficiency (e.g., leg swelling) by strengthening vessel walls and improving microcirculation.

Özellikle ilgili olduğu kişiler: Adults with venous insufficiency or mild circulation issues

5 · PubMed (Venous Insufficiency Meta-analysis)

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally safe for short-term use at recommended doses; main concerns are rare liver effects, skin allergy, and sedation.

Uyarılar

Most side effects are mild and transient (GI upset, headache, skin rash).
Rare reports of liver toxicity; risk is higher in those with pre-existing liver conditions or when combined with hepatotoxic drugs.
May enhance sedative effects of some medications.
Avoid use in pregnancy or breastfeeding due to insufficient safety data.
Do not use Gotu Kola if you have liver disease or a history of liver dysfunction.
Avoid use with sedative medications due to potential additive effects.
Monitor for allergic skin reactions; discontinue if rash develops.
Consult a healthcare provider before combining with hepatotoxic drugs.

İlaçlarla bilinen etkileşimler

Sedatives (additive CNS depression)
Hepatotoxic drugs (increased liver risk)

Kontrendikasyonlar / özel dikkat gerektiren gruplar

Pregnancy
Breastfeeding
Liver disease

etkileşimler

Etkin madde ↔ takviye / ilaç / gıda arasındaki önemli etkileşimler

Gotu Kola may interact with sedatives, hepatotoxic drugs, and agents affecting liver metabolism.

Pairing with sedatives may increase risk of drowsiness or CNS depression.

drug · sedatives

CautionModerate

Neden

Gotu Kola may enhance sedative effects of medications such as benzodiazepines or barbiturates.

Öneri

Avoid or use only under supervision.

1 · WebMD 6 · NIH NCCIH

Combining with other hepatotoxic agents increases liver risk.

drug · hepatotoxic medications

AvoidLimited

Neden

Rare cases of liver toxicity have been reported; risk may rise with other drugs that affect the liver.

Öneri

Avoid combination or monitor liver function closely.

1 · WebMD 6 · NIH NCCIH

Not recommended in individuals with existing liver disease.

lifestyle · liver disease

AvoidLimited

Neden

Case reports describe liver injury linked to Gotu Kola, especially in at-risk individuals.

Öneri

Do not use if you have a history of liver problems.

1 · WebMD 6 · NIH NCCIH

Etki mekanizmaları

Nasıl çalıştığına dair kısa açıklamalar

Enhancement of Collagen Synthesis

Active triterpenoids stimulate fibroblast activity and collagen production, aiding wound healing and skin repair.

4 · PubMed (Wound/Ulcer Study)

Modulation of Neurotransmitter Systems and Cerebral Blood Flow

May raise antioxidant levels and alter neurotransmitter function, enhancing memory and attention.

2 · PubMed (Cognitive Study)

Strengthening of Vascular Endothelium

Increases microcirculatory integrity and reduces capillary leakage, benefiting venous insufficiency.

5 · PubMed (Venous Insufficiency Meta-analysis)

Kaynaklar ve Referanslar

Bu ifadelerin dayandığı birincil kaynaklar ve incelemeler

6 sources

WebMD

PubMed (Cognitive Study)

PubMed (Anxiety Study)

PubMed (Wound/Ulcer Study)

PubMed (Venous Insufficiency Meta-analysis)

NIH NCCIH

Son güncelleme: 7 Şubat 2026

Bu bilgiler yalnızca bilgilendirme amaçlıdır ve tıbbi tavsiye yerine geçmez.

Tüm besinler

Botanicals & Natural Substances

164 kayıt

Gotu KolaExtract

Açıklama

Avantajlar

Cognitive Enhancement

Anxiety Reduction

Wound Healing and Skin Repair

Supports Circulation and Venous Health

Güvenlik ve Uyarılar

etkileşimler

Pairing with sedatives may increase risk of drowsiness or CNS depression.

Combining with other hepatotoxic agents increases liver risk.

Not recommended in individuals with existing liver disease.

Etki mekanizmaları

Enhancement of Collagen Synthesis

Modulation of Neurotransmitter Systems and Cerebral Blood Flow

Strengthening of Vascular Endothelium

Kaynaklar ve Referanslar

Botanicals & Natural Substances

Diğer kategoriler

Güvenlik ve Uyarılar

etkileşimler

Pairing with sedatives may increase risk of drowsiness or CNS depression.

Combining with other hepatotoxic agents increases liver risk.

Not recommended in individuals with existing liver disease.

Etki mekanizmaları

Enhancement of Collagen Synthesis

Modulation of Neurotransmitter Systems and Cerebral Blood Flow

Strengthening of Vascular Endothelium

Kaynaklar ve Referanslar

Gotu Kola
Extract