Apigenin is a natural plant flavonoid found in foods such as parsley, celery, and chamomile. It is also available as a dietary supplement.

What are the potential benefits of apigenin?

Apigenin is studied for antioxidant and anti-inflammatory effects and for supporting relaxation and sleep. Experimental research also explores anticancer activity, but human clinical evidence is limited.

How much apigenin should I take?

Common supplemental amounts are about 50–100 mg per day. Individual needs vary, so consider starting low and consult a clinician if you have medical conditions.

Does apigenin help with anxiety or sleep?

Apigenin may promote relaxation through effects on GABA-related pathways, and chamomile extracts containing apigenin have been studied for mild anxiety and sleep support. Results can vary between individuals.

Is apigenin safe and are there interactions?

Apigenin from foods is generally well tolerated, while supplement safety depends on dose and individual factors. If you are pregnant, breastfeeding, or taking medications, consult a healthcare professional due to potential interactions.

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Apigenin

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Apigenin is a natural plant flavonoid studied for its antioxidant, anti-inflammatory, calming, and anticancer properties.

Longevity Sleep Improvement Anti-inflammatory Cancer-inhibitor Stress Relief Antioxidant Anxiety Relief

Doz aralığı

50–100 mg

Taken once daily, preferably in the evening.

Gelir

Take with a small meal or as directed by a healthcare professional. Consuming with food may aid absorption.

Yağda çözünmez.

En iyi zaman

Often taken in the evening or before sleep to leverage calming effects.

Açıklama

Apigenin is a flavonoid found in foods like parsley, celery, and chamomile. It is available as a supplement, most commonly used to reduce inflammation, relieve mild anxiety, and promote relaxation or sleep.

Avantajlar

Kanıt derecesi ile ana etkiler

Limited

Kanıtla ilgili not

Preclinical and early human studies suggest potential for inflammation and anxiety support, but robust clinical evidence is limited.

May reduce inflammation

Limited

Preclinical studies and limited human evidence suggest apigenin can reduce biomarkers of inflammation, possibly aiding inflammatory conditions.

Özellikle ilgili olduğu kişiler: Adults seeking anti-inflammatory support

S2 · PubMed – Anti-inflammatory activity of apigenin S8 · International Journal of Molecular Sciences – Apigenin and inflammation

May relieve mild anxiety and aid sleep

Limited

Evidence from clinical trials in chamomile extract and animal studies indicates apigenin may reduce mild anxiety and promote relaxation or sleep, likely via GABAergic pathways.

Özellikle ilgili olduğu kişiler: Adults with mild anxiety or sleep disturbances

S3 · PubMed – Apigenin for anxiety: Chamomile extract clinical trial S5 · Examine.com – Apigenin

Experimental anticancer activity

Theoretical

Laboratory and animal studies show apigenin may inhibit the growth and spread of various cancer cells, mainly by inducing apoptosis and modulating cell signaling; human clinical data is lacking.

Özellikle ilgili olduğu kişiler: Individuals interested in cancer prevention (experimental)

S4 · Cancer Letters – Anticancer mechanisms of apigenin S5 · Examine.com – Apigenin

Antioxidant support

Limited

Acts as an antioxidant, scavenging free radicals and supporting cellular health; primary evidence is from preclinical studies.

Özellikle ilgili olduğu kişiler: Adults seeking antioxidant support

S1 · NIH Office of Dietary Supplements – Flavonoids Fact Sheet S6 · Molecules – Bioavailability and food sources of apigenin

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally well-tolerated at typical doses, but caution is advised in sensitive groups and when combined with certain medications.

Uyarılar

Adverse effects are rare but can include allergic reactions and increased drowsiness if combined with sedatives.
Long-term safety has not been established, especially at high doses.
Avoid use during pregnancy and breastfeeding due to insufficient safety data.
Consult a healthcare provider before use if taking sedatives, anticoagulants, or antiplatelet drugs due to potential interactions.
Avoid if allergic to chamomile or related plants (Asteraceae/Compositae family).

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