Spermidine
Spermidine is a natural polyamine shown to support cellular health, longevity, and cardiovascular and brain function, mainly by promoting autophagy.
Spermidine is a polyamine compound present in all living cells and abundant in certain foods such as wheat germ and soybeans. It is increasingly researched for its role in supporting healthy aging and cellular maintenance through the induction of autophagy.
Most clinical data are preliminary or from small-scale studies, but animal research and human observational data support potential benefits, particularly for cardiovascular health and cellular aging.
Supports healthy aging and longevity
ModerateSpermidine may slow cellular aging and extend lifespan primarily by inducing autophagy, a process that helps clear damaged cellular components.
Cardiovascular protection
ModerateSupplementation is associated with improved cardiac function and lower risk of cardiovascular disease, likely through the support of vascular integrity and reduced inflammation.
May support cognitive and neuroprotective functions
LimitedSpermidine may promote brain health by reducing neuroinflammation and supporting autophagy in neurons, potentially lowering the risk of neurodegeneration.
Immune support
LimitedMay enhance immunological memory by promoting memory T-cell formation and rejuvenating immune cell function.
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