Cynarin is a phenolic compound found mainly in artichoke leaves (Cynara scolymus). It is commonly included in supplements aimed at supporting digestion and liver function.

What are the potential benefits of cynarin?

Cynarin (often as part of artichoke extract) is associated with antioxidant activity, bile-stimulating effects, and potential support for liver enzyme balance. It may also support cholesterol and triglyceride management in some people.

How does cynarin support digestion?

Cynarin can stimulate bile production and flow, which helps the body digest fats. This may reduce indigestion symptoms such as bloating or post-meal discomfort.

What is a typical cynarin dosage?

Supplement dosages commonly fall around 8–32 mg of cynarin per day, depending on the product and standardization. Follow the label directions and consider medical advice if you have liver or gallbladder conditions.

Is cynarin safe, and who should avoid it?

Cynarin is generally used as part of artichoke leaf supplements, but it may not be suitable for people with bile duct obstruction or certain gallbladder problems. Those who are pregnant, breastfeeding, or taking medications should consult a clinician before use.

Bilimsel destekli 313 besin

3251 kaynak incelendi

Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Besin bul

Popüler seçimler

Eicosapentaenoic acid (EPA)Vitamin D3 Docosahexaenoic acid (DHA)Zinc (Bisglycinate)

Toplam 313 besin

Vitamin B

Vitamin B1 (Thiamine)

Vitamin B2 (Riboflavin)

Vitamin B3 (Niacin)

Vitamin B5 (Pantothenic Acid)

Vitamin B6 (Pyridoxine)

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin B12 (Methylcobalamin)

Vitamin B12 (Cobalamin)

Vitamin A & Carotenoids

Vitamin C

Vitamin D

Vitamin E

Vitamin K

Vitaminoids

Trimethylglycine (Betaine)

NMN (Nicotinamide Mononucleotide)

Pyrroloquinoline Quinone (PQQ)

D-Chiro-Inositol

Coenzym Q10 (Ubiquinone)

Betaine HCL

Nicotinamide Riboside

Vitamin B8 (Myo-Inositol)

Choline

Citicoline (CDP-Choline)

Coenzyme Q10 (Ubiquinol)

Calcium

Calcium Alpha-Ketoglutarate

Magnesium

Magnesium Bisglycinate

Magnesium L-Threonate

Trace Minerals

Copper (Bisglycinate)

Chromium Picolinate

Manganese (Bisglycinate)

Zinc

Pentadecanoic Acid (C15:0)

Phosphatidylserine

R-Alpha Lipoic Acid

Black Cumin Oil

Extra Virgin Olive Oil

Ceratiq wheat oil extract

Phospholipids

Algae Oil

Fish Oil

Conjugated Linoleic Acid

Gamma-Aminobutyric Acid

Alpha-Linolenic Acid

Gamma-Linolenic Acid

Omega-3

Docosapentaenoic acid (DPA)

Eicosapentaenoic acid (EPA)

Docosahexaenoic acid (DHA)

AminoMar

Acetyl-L-Carnitine

PABA (para-aminobenzoic acid)

Essential Amino Acids

Conditionally Essential Amino Acids

L-Theanine

Non-Essential Amino Acids

Beta-Alanine

L-Cysteine Hydrochloride

Amino Acid Derivative

Taurine

Creatine (Hydrochloride)

L-Arginine Alpha-Ketoglutarate

Creatine (Monohydrate)

Akkermansia muciniphila

Lactobacillus Reuteri

Probiotics

Bifidobacterium longum BB536

Prebiotics

Stinging Nettle Extract

Pomegranate Polyphenols

Red Beet Extract

Pine Extract (Pycnogenol)

Oligomeric Proanthocyanidins (OPC)

Ashwagandha Root Extract

Methylsulfonylmethane (MSM)

Citrus Sinensis Extract

Horsetail Stem Extract

Flax Seed Extract

Sulforaphane Glucosinolate

Garlic Extract

Black Pepper

Apricot Kernel Extract

Lovage

Spiny Rest Harrow Root Extract

Juniper Berry Extract

Bearberry Leaf Extract

White Kidney Bean Extract

Lady’s Mantle Extract

Bitter Orange Extract

St. John’s Wort Extract

Japanese Knotweed Extract

Hydroxytyrosol/tyrosol

Olive extract

Sesame seed lignan extract

Broccoli Sprout Extract

Cranberry Extract

Flavon Glycosides

Gentian Root Extract

Griffonia simplicifolia Extract

Ajuga Turkestanica Extract

Amaranthus Leaf Extract

Banaba Extract

Boswellia Extract

Capsaicin

Cayenne Pepper Extract

Celery Extract

Ceylon Cinnamon Extract

Chamomile Extract

Charantin

Chinese Goldthread Root Extract

Citrus Aurantium Extract

Cocoa Extract

Cyanotis Arachnoidea Extract

Fadogia Agrestis Extract

Garcinia Cambogia Extract

Goldenrod Extract

Green Tea Extract

Guarana Extract

Horse Chestnut Extract

Grapefruit Seed Extract

Grape Vine Leaf Extract

Green Tea Polyphenols

Epigallocatechin Gallate (EGCG)

Adaptogens

Cordyceps sinensis extract

Ginsenoside

Lion's Mane (Hericium erinaceus)

Ginseng Extract

Cat's Claw (Uncaria tomentosa)

Arjuna (Terminalia arjuna)

Tribulus Terrestris Extract

Rhodiola rosea

Panax Ginseng Extract

Mushrooms

Reishi Extract

Astragalus Polysaccharides

Hyaluronic Acid

Glucosamine Sulfate

Chondroitin Sulfate

Glucosamine Sulphate 2KCL

Cynarin

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Phenolic compound from artichoke leaves with antioxidant, choleretic, and potential liver-protective effects.

Digestion & Gut Health Anti-inflammatory Antioxidant Liver Health Gallbladder Support Cholesterol Management

Doz aralığı

8–32 mg

Divided in 2–3 daily doses with meals.

Gelir

Take with meals to promote bile flow and reduce potential digestive discomfort. Usually as part of an artichoke leaf extract standardized to 2.5–5% cynarin.

Yağda çözünmez.

En iyi zaman

Best taken with main meals (breakfast/lunch/dinner) for digestive benefits. Separate from bile acid sequestrants.

Açıklama

Cynarin is a bioactive molecule found mainly in artichoke leaves (Cynara scolymus). It is known for its antioxidant, choleretic (bile-stimulating), and potential hepatoprotective properties, and often used in supplements targeting liver and digestive health.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Most evidence comes from studies of artichoke extract, of which cynarin is a key active component, rather than isolated cynarin. Effects on liver enzymes, digestion, and cholesterol have supporting clinical trial data, but research on isolated cynarin in humans is limited.

Supports Liver Enzyme Balance

Moderate

Cynarin, via artichoke extract, may help lower elevated liver enzymes (ALT, AST) in non-alcoholic fatty liver disease (NAFLD) and other mild liver dysfunctions, suggesting support for normal liver function.

Özellikle ilgili olduğu kişiler: Individuals with elevated liver enzymes · NAFLD patients

S3 · PMCID: PMC9348909 — Effects of Cynara scolymus L. supplementation on liver enzymes: A systematic review and meta-analysis of randomized controlled trials S7 · Examine.com: Artichoke Extract S6 · NIH LiverTox: Artichoke (Cynara scolymus)

Cholesterol and Lipid Management

Moderate

Artichoke-derived cynarin may contribute to modest reductions in total cholesterol, LDL cholesterol, and triglycerides, attributed to inhibition of cholesterol synthesis and increased bile excretion.

Özellikle ilgili olduğu kişiler: Those with mildly elevated cholesterol · General cardiovascular support

S4 · PubMed PMID: 28609140 — Efficacy of artichoke leaf extract on lipid profiles: a systematic review and meta-analysis S7 · Examine.com: Artichoke Extract S8 · EFSA (European Food Safety Authority): Artichoke Leaf

Digestive Aid and Bile Flow

Limited

Cynarin stimulates bile production, which can improve fat digestion and alleviate symptoms of indigestion such as bloating and discomfort.

Özellikle ilgili olduğu kişiler: Individuals with sluggish digestion or mild dyspepsia

S1 · WebMD: Artichoke S7 · Examine.com: Artichoke Extract

Antioxidant and Anti-Inflammatory Effects

Limited

Cynarin exhibits antioxidant activity and may have anti-inflammatory effects by reducing free radicals and inflammatory signaling in vitro.

Özellikle ilgili olduğu kişiler: General prevention · Those seeking antioxidant support

S5 · PMCID: PMC6271736 — Anti-inflammatory and antioxidant activities of artichoke phenolic compounds S7 · Examine.com: Artichoke Extract

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally well-tolerated at supplemental dosages as part of artichoke extract, but possible risks for individuals with bile duct conditions or allergies.

Uyarılar

Rare mild gastrointestinal symptoms (gas, cramping) may occur.
Allergy risk for those sensitive to Asteraceae (daisy) family plants.
Not advised for persons with bile duct obstruction or gallstones except under medical supervision.
Avoid if allergic to plants in the Asteraceae (daisy) family due to risk of allergic reaction.
Do not use if you have bile duct obstruction or gallstones without medical supervision.
Use with caution if you have known cholelithiasis or cholangitis, and seek clinician guidance.

İlaçlarla bilinen etkileşimler