Methylsulfonylmethane
(MSM)
MSM is a naturally occurring sulfur compound used as a supplement primarily for joint pain and inflammation.
Methylsulfonylmethane (MSM) is an organic sulfur compound found naturally in plants and animals. As a dietary supplement, MSM is widely used for joint health, inflammation reduction, and skin support, with growing clinical evidence supporting these uses.
There is moderate-quality clinical evidence for MSM’s benefits in osteoarthritis, joint pain, exercise recovery, and skin health, but large-scale, long-term trials are limited.
Reduces joint pain and improves function in osteoarthritis
ModerateMSM supplementation may modestly reduce pain and improve physical function in people with knee osteoarthritis.
Decreases exercise-induced muscle damage and soreness
ModerateMSM may help reduce markers of muscle damage and perceived soreness after strenuous exercise, aiding recovery.
Supports skin health and appearance
LimitedOral and topical MSM may improve skin elasticity, firmness, and hydration, partially by supporting collagen and keratin production.
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