What is grape vine leaf extract?

Grape vine leaf extract is made from the leaves of Vitis vinifera. It contains polyphenols and flavonoids that provide antioxidant and anti-inflammatory activity.

What is grape vine leaf extract used for?

It is commonly used to support symptoms of chronic venous insufficiency (CVI), such as leg heaviness, pain, and swelling. It may also be used for general vascular support.

Does grape vine leaf extract help with leg swelling?

It may help reduce leg edema, including ankle or calf swelling, particularly when related to venous issues such as varicose veins or prolonged standing.

What is a typical dosage for grape vine leaf extract?

Common supplemental amounts are in the range of 360–720 mg per day. Follow the product label and consult a clinician if you have medical conditions or take medications.

Who should be cautious with grape vine leaf extract?

People who are pregnant or breastfeeding, have bleeding disorders, or take anticoagulant or antiplatelet medications should consult a healthcare professional before use. Stop use and seek advice if you develop unusual bleeding or allergic reactions.

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Grape Vine
Leaf Extract

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

Extract of Vitis vinifera leaves, used for chronic venous insufficiency and vascular support due to its antioxidant and anti-inflammatory properties.

Longevity Anti-inflammatory Cardiovascular Support Antioxidant

Doz aralığı

360–720 mg

Divided into 2 doses per day, often morning and with later meal

Gelir

Take with meals to enhance absorption and reduce GI discomfort.

Yağda çözünmez.

En iyi zaman

Bioavailability is improved with food; take at roughly the same time each day for consistency.

Açıklama

Grape vine leaf extract is derived from Vitis vinifera and traditionally used to treat symptoms of chronic venous insufficiency (CVI) like leg pain, heaviness, and swelling. It is rich in polyphenols and flavonoids, conferring antioxidant and anti-inflammatory effects that may benefit cardiovascular and vascular health.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Clinical trials support its effectiveness in CVI; antioxidant benefits are mechanistically supported and studied in animals and in vitro.

Alleviates symptoms of chronic venous insufficiency (CVI)

Moderate

Reduces leg pain, swelling, and heaviness in individuals with CVI by improving venous tone and decreasing capillary permeability.

Özellikle ilgili olduğu kişiler: Adults with mild-to-moderate CVI · Individuals with venous leg symptoms

1 · PubMed: Red vine leaf extract in chronic venous insufficiency 2 · PubMed: Clinical efficacy of red vine leaf extract in CVI

Reduces leg swelling and edema

Moderate

Helps decrease calf and ankle swelling in people with leg edema, particularly in those with varicose veins or who stand for prolonged periods.

Özellikle ilgili olduğu kişiler: Individuals with leg edema or varicose veins

2 · PubMed: Clinical efficacy of red vine leaf extract in CVI

Provides antioxidant and anti-inflammatory support

Limited

Supplying flavonoids and polyphenols, it helps neutralize free radicals and reduce inflammation, potentially supporting cardiovascular and general health.

Özellikle ilgili olduğu kişiler: People seeking antioxidant support

3 · PubMed: Antioxidant activity of grape vine leaf 5 · Examine.com: Red vine leaf extract

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally well tolerated in studied doses, but monitoring is advised for at-risk populations.

Uyarılar

Avoid use in individuals allergic to grapes or grape-derived products.
Do not use in pregnancy or lactation due to limited safety data.
Monitor for possible bleeding if taking anticoagulant medications.
Avoid if allergic to grapes or grape-derived products.
Do not use during pregnancy or breastfeeding due to insufficient safety data.
Use only with clinician supervision if taking anticoagulant or antiplatelet medications (possible increased bleeding risk).

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