What is sulforaphane?

Sulforaphane is an isothiocyanate formed from glucoraphanin in cruciferous vegetables, especially broccoli sprouts. It is known for activating cellular defense pathways involved in antioxidant and detoxification responses.

What are the potential benefits of sulforaphane?

Research suggests it may support antioxidant defenses, phase II detox enzymes, and inflammation modulation. It is also studied for potential roles in cardiometabolic and neuroprotective support, with evidence varying by condition and product.

What is a typical sulforaphane dosage?

Common supplemental ranges are about 20–100 mg per day, depending on the product and its sulforaphane yield. Start low and follow the label, especially if using concentrated extracts.

How do broccoli sprouts produce sulforaphane?

Sulforaphane is produced when the enzyme myrosinase converts glucoraphanin after the plant is chopped, chewed, or otherwise damaged. Some supplements include myrosinase or rely on gut conversion, which can affect consistency.

Is sulforaphane safe for everyone?

Sulforaphane from foods is generally well tolerated, while supplements may cause gastrointestinal upset in some people. If you are pregnant, breastfeeding, have a thyroid condition, or take medications, consult a clinician before using high-dose supplements.

Bilimsel destekli 313 besin

3251 kaynak incelendi

Kanıta dayalı bilgiler

Hedefe veya kategoriye göre keşfet

Besin bul

Popüler seçimler

Eicosapentaenoic acid (EPA)Vitamin D3 Docosahexaenoic acid (DHA)Zinc (Bisglycinate)

Toplam 313 besin

Vitamin B

Vitamin B1 (Thiamine)

Vitamin B2 (Riboflavin)

Vitamin B3 (Niacin)

Vitamin B5 (Pantothenic Acid)

Vitamin B6 (Pyridoxine)

Vitamin B7 (Biotin)

Vitamin B9 (Folic Acid)

Vitamin B12 (Methylcobalamin)

Vitamin B12 (Cobalamin)

Vitamin A & Carotenoids

Vitamin C

Vitamin D

Vitamin E

Vitamin K

Vitaminoids

Trimethylglycine (Betaine)

NMN (Nicotinamide Mononucleotide)

Pyrroloquinoline Quinone (PQQ)

D-Chiro-Inositol

Coenzym Q10 (Ubiquinone)

Betaine HCL

Nicotinamide Riboside

Vitamin B8 (Myo-Inositol)

Choline

Citicoline (CDP-Choline)

Coenzyme Q10 (Ubiquinol)

Calcium

Calcium Alpha-Ketoglutarate

Magnesium

Magnesium Bisglycinate

Magnesium L-Threonate

Trace Minerals

Copper (Bisglycinate)

Chromium Picolinate

Manganese (Bisglycinate)

Zinc

Pentadecanoic Acid (C15:0)

Phosphatidylserine

R-Alpha Lipoic Acid

Black Cumin Oil

Extra Virgin Olive Oil

Ceratiq wheat oil extract

Phospholipids

Algae Oil

Fish Oil

Conjugated Linoleic Acid

Gamma-Aminobutyric Acid

Alpha-Linolenic Acid

Gamma-Linolenic Acid

Omega-3

Docosapentaenoic acid (DPA)

Eicosapentaenoic acid (EPA)

Docosahexaenoic acid (DHA)

AminoMar

Acetyl-L-Carnitine

PABA (para-aminobenzoic acid)

Essential Amino Acids

Conditionally Essential Amino Acids

L-Theanine

Non-Essential Amino Acids

Beta-Alanine

L-Cysteine Hydrochloride

Amino Acid Derivative

Taurine

Creatine (Hydrochloride)

L-Arginine Alpha-Ketoglutarate

Creatine (Monohydrate)

Akkermansia muciniphila

Lactobacillus Reuteri

Probiotics

Bifidobacterium longum BB536

Prebiotics

Stinging Nettle Extract

Pomegranate Polyphenols

Red Beet Extract

Pine Extract (Pycnogenol)

Oligomeric Proanthocyanidins (OPC)

Ashwagandha Root Extract

Methylsulfonylmethane (MSM)

Citrus Sinensis Extract

Horsetail Stem Extract

Flax Seed Extract

Sulforaphane Glucosinolate

Garlic Extract

Black Pepper

Apricot Kernel Extract

Lovage

Spiny Rest Harrow Root Extract

Juniper Berry Extract

Bearberry Leaf Extract

White Kidney Bean Extract

Lady’s Mantle Extract

Bitter Orange Extract

St. John’s Wort Extract

Japanese Knotweed Extract

Hydroxytyrosol/tyrosol

Olive extract

Sesame seed lignan extract

Broccoli Sprout Extract

Cranberry Extract

Flavon Glycosides

Gentian Root Extract

Griffonia simplicifolia Extract

Ajuga Turkestanica Extract

Amaranthus Leaf Extract

Banaba Extract

Boswellia Extract

Capsaicin

Cayenne Pepper Extract

Celery Extract

Ceylon Cinnamon Extract

Chamomile Extract

Charantin

Chinese Goldthread Root Extract

Citrus Aurantium Extract

Cocoa Extract

Cyanotis Arachnoidea Extract

Fadogia Agrestis Extract

Garcinia Cambogia Extract

Goldenrod Extract

Green Tea Extract

Guarana Extract

Horse Chestnut Extract

Grapefruit Seed Extract

Grape Vine Leaf Extract

Green Tea Polyphenols

Epigallocatechin Gallate (EGCG)

Adaptogens

Cordyceps sinensis extract

Ginsenoside

Lion's Mane (Hericium erinaceus)

Ginseng Extract

Cat's Claw (Uncaria tomentosa)

Arjuna (Terminalia arjuna)

Tribulus Terrestris Extract

Rhodiola rosea

Panax Ginseng Extract

Mushrooms

Reishi Extract

Astragalus Polysaccharides

Hyaluronic Acid

Glucosamine Sulfate

Chondroitin Sulfate

Glucosamine Sulphate 2KCL

Sulforaphane

Orta düzeyde araştırma durumu·7/10

Daha yüksek puan, daha iyi bir çalışma durumuna işaret eder, ancak mutlaka etkinlik anlamına gelmez.

A phytochemical in broccoli sprouts, sulforaphane is a researched antioxidant with roles in detoxification, inflammation modulation, and cellular protection.

Anti-Aging Anti-inflammatory Cardiovascular Support Cancer-inhibitor Antioxidant Neuroprotective

Doz aralığı

20–100 mg

Once daily

Gelir

Take with a source of myrosinase (raw cruciferous vegetables or supplements with active myrosinase enzyme) to enhance absorption.

Yağda çözünmez.

En iyi zaman

Preferably with or around a meal containing cruciferous vegetables; morning or first meal.

Açıklama

Sulforaphane is an isothiocyanate found in cruciferous vegetables, particularly broccoli sprouts. It is known for activating cellular defense pathways that combat oxidative stress and inflammation, and is taken for potential prevention and support in cancer, cardiovascular, and neurodegenerative conditions.

Avantajlar

Kanıt derecesi ile ana etkiler

Moderate

Kanıtla ilgili not

Animal and preclinical trials show promising effects for various health endpoints, while human studies support safety and some benefits, but more large-scale clinical trials are needed.

Supports cellular detoxification and antioxidant defense

Strong

Sulforaphane activates Nrf2 pathways, boosting phase II detox enzymes and antioxidants, helping protect against oxidative damage.

Özellikle ilgili olduğu kişiler: General adult · Individuals seeking oxidative stress protection

1 · PubMed Review: Sulforaphane and Human Health 4 · PubMed Review: Sulforaphane as an Antioxidant 5 · Examine: Sulforaphane Overview

Potential cancer risk reduction

Moderate

High intake is associated with reduced cancer risk, possibly due to influences on carcinogen metabolism and cell protection, though evidence is strongest for cruciferous vegetables overall, not isolated SFN supplements.

Özellikle ilgili olduğu kişiler: Individuals at risk for certain cancers

1 · PubMed Review: Sulforaphane and Human Health 3 · NIH: Cruciferous Vegetables and Cancer Prevention 7 · Cochrane Review: Dietary Interventions in Cancer Prevention

Neuroprotective and cognitive support

Limited

May reduce neuroinflammation and has shown modest improvements in social interaction and behavior in some populations with autism spectrum disorder.

Özellikle ilgili olduğu kişiler: Neurodevelopmental disorder care · Brain health support

2 · Clinical Trial: Sulforaphane in Autism Spectrum Disorder 5 · Examine: Sulforaphane Overview

Anti-inflammatory effects

Moderate

Reduces markers of inflammation in preclinical and some human studies.

Özellikle ilgili olduğu kişiler: Individuals with inflammatory or metabolic conditions

1 · PubMed Review: Sulforaphane and Human Health 4 · PubMed Review: Sulforaphane as an Antioxidant 5 · Examine: Sulforaphane Overview

Supports cardiovascular health

Limited

Consumption is associated with improved endothelial function and blood pressure in some studies.

Özellikle ilgili olduğu kişiler: Cardiovascular Support

1 · PubMed Review: Sulforaphane and Human Health 5 · Examine: Sulforaphane Overview

Güvenlik ve Uyarılar

Önemli güvenlik bilgileri ve bilinen riskler

Sadece eğitim amaçlıdır • tıbbi tavsiye değildir

Generally safe at recommended doses; higher doses may increase risk of stomach upset or impact thyroid in sensitive groups.

Uyarılar

Mild GI symptoms (nausea, diarrhea) have been reported at higher supplemental intakes.
May reduce iodine uptake and influence thyroid function, especially in those with thyroid disorders or marginal iodine status.
No known significant drug interactions, but overall clinical evidence is still emerging.
Avoid excessive sulforaphane if you have a thyroid disorder unless advised by a clinician.
Use with caution during pregnancy and lactation; consult a healthcare provider first.
Monitor for gastrointestinal upset and reduce dose or discontinue if severe symptoms occur.

İlaçlarla bilinen etkileşimler